Going from South to North, US Highway 17, begins on the Gulf Coast of Florida at its junction with US 41 near Interstate 75 in Punta Gorda, FL in Charlotte County. From there, US 17 follows a generally North or North Easterly path roughly parallel with Interstate 4 through the towns and cities of Winter Haven, Kissimmee, Orlando, Winter Park and Sanford. US 92 will join with US 17 at Lake Alford, FL near Tampa and will share pavement with US 17 through Orlando and Sanford and on to Deland, Fl, where US 92 continues east to Daytona Beach. From Deland, US 17 will continue Northward along the St. Johns River through Palatka, Orange Park and Jacksonville where the St. John's River turns East to the Ocean. US 17 will continue North from Jacksonville to Yulee, FL where it will take a turn Northwest following the St. Marys River and the Georgia Florida Border. After crossing Interstate 95, US 17 will take a turn North and cross the St. Mary's River and enter Georgia via the bridge shown below.
Source(es): Google Maps, http://en.wikipedia.org/wiki/U.S._Route_17